334 posters, 125 sessions, 831 authors, 236 institutions
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78th Annual PostGraduate Assembly in Anesthesiology (PGA78) 2024
December 6 - 9, 2024 | New York City

5014
Cut Ketamine Dilution & Concentration Errors
Part of Topic
Cut Ketamine Dilution & Concentration Errors
Intervention:
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Based on hospital ketamine inventory data, a multi-intervention collaboration with Pharmacy was developed to increase ease of access without compromising patient safety
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Planned interventions include:
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substitution to prefilled, prediluted ready-to-administer syringes in all studied locations
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decreased stock of 200 mg/20 mL and 500 mg/10mL vials
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maintained in the event of supply issues
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removal of all 500 mg/5mL vials
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The new prefilled ketamine syringe stock will be standardized across all procedural rooms
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improving provider satisfaction and decreasing burnout, a known predictor of medication administration errors
Outcomes:
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Standardized placement of ketamine vials and substitution to prefilled-syringes leads to:
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Increased ease of access
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Streamlined care
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Increased likelihood that ketamine will be used as a perioperative opioid-sparing pain adjunct
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Decreased peri and post-operative opioid use
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Improved postoperative pain control
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Increased patient and provider satisfaction
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Patient safety is addressed by minimizing opportunity for human error, specifically within an academic environment
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Chaouch MAMA, Daghmouri MA, Boutron MC, et al. Ketamine as a component of multimodal analgesia for pain management in bariatric surgery: A systematic review and meta-analysis of randomized controlled trials. Ann Med Surg (Lond). 2022;78:103783. Published 2022 May 14. doi:10.1016/j.amsu.2022.103783
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Stojanović M, Marinković M, Miličić B, et al. The Role of Ketamine as a Component of Multimodal Analgesia in Burns: A Retrospective Observational Study. J Clin Med. 2024;13(3):764. Published 2024 Jan 29. doi:10.3390/jcm13030764
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Wang X, Lin C, Lan L, Liu J. Perioperative intravenous S-ketamine for acute postoperative pain in adults: A systematic review and meta-analysis. J Clin Anesth. 2021;68:110071. doi:10.1016/j.jclinane.2020.110071
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Whitaker DK, Lomas JP. Time for prefilled syringes - everywhere. Anaesthesia. 2024;79(2):119-122. doi:10.1111/anae.16181
