78th Annual PostGraduate Assembly in Anesthesiology (PGA78) 2024

Anesthetic Considerations for Diagnosed Creutzfeldt-Jakob Disease

Creutzfeldt-Jakob Disease (CJD) is a rare, progressive neurodegenerative disorder characterized by rapid cognitive decline and neurological impairment, typically leading to death within months. CJD is classified into four forms: sporadic CJD, genetic CJD, variant CJD (vCJD), and iatrogenic CJD. [1,2]

•Sporadic CJD, the most common form, typically affects individuals over 60 but can also present in younger patients, as seen in this case.

•Genetic CJD is inherited and typically presents earlier in life.

•vCJD, associated with prion transmission through contaminated food, primarily affects younger individuals.

•Iatrogenic CJD results from medical procedures involving prion-contaminated equipment.

Anesthetic management for CJD patients is complex due to risks of neurotoxicity from anesthetics and prion transmission during medical procedures. Given the rapid progression of the disease, anesthetic techniques must be carefully tailored to minimize complications.

This case report discusses a 33-year-old female with sporadic CJD undergoing dilation and evacuation following intrauterine fetal demise, highlighting key anesthetic considerations and protocols.

78th Annual PostGraduate Assembly in Anesthesiology (PGA78) 2024

Anesthetic Considerations for Diagnosed Creutzfeldt-Jakob Disease

Poster Presenter

Authors

Affiliations

Part of Topic