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4026

Deep Sedation Technique For Outpatient Brachytherapy: A Single Center Experience

Part of Topic

Deep sedation technique for outpatient brachytherapy: A single center experience 

Katherine Herrera, MD; Irene Osborn, MD

Background

  • Cervical cancer has moved up to become the 3rd most common cancer death among young women in the U.S.

  • Providing anesthetic care for GYN brachytherapy is beneficial for optimal treatment & patient comfort since it requires immobility & analgesia for a prolonged period of time. 

  • Current guidelines from the ABS & ASA do not specify a preferred anesthesia approach nor type of anesthesia modality for GYN  brachytherapy applicator placement.

Objective: Determine the optimal deep sedation & analgesia for patients receiving hybrid intracavitary/interstitial high-dose rate (HDR) brachytherapy with GYN cancers, as a non-OR procedure (with no room for an anesthesia machine), employing monitored anesthesia care (MAC) with a deep sedation technique using the jaw elevation device (JED). 

Methodology

Retrospective data from anesthesia records (2019-2022)

  1. Lithotomy position, head/neck on the JED, CO2 filter line, O2 at 2 L/min, pulse ox, ECG, B.P. cuff

  2. Meds administered: sedation (midazolam), analgesia (fentanyl), antiemetics, propofol/dexmedetomidine infusion. Younger pts: given a bolus (or several) of ketamine

  3. Near-end of procedure: IV acetaminophen/ketorolac

  4. Recovery room for 2 hrs → post-procedural eval.

Results
  • Awake, alert, spontaneous breathing, hemodynamically stable, no anesthetic complications nor POVN

  • 8 (27.6%) of 29 patients reported a higher pain status in session 1 and/or 2

Conclusions
  • Brachytherapy presents the anesthesiology team with unique challenges, different from the surgical patients in the OR. 

  • Adequate conditions include complete staffing, technical equipment, application of the right technique with experienced anesthesia teams is critical for both the patient and the radiation oncologists.

  • Our study suggest that this deep sedation & analgesia technique using MAC with the JED offers safe/effective pain control for undergoing brachytherapy for GYN malignancies, with minimal or no post-procedural complications, and allows for outpatient, same-day home discharge. 

  • Further research is required in this area in order to optimize analgesia in this patient population.


78th Annual PostGraduate Assembly in Anesthesiology (PGA78) 2024 » banner
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