Not as safe as we thought

• Cannabis is consumed for both recreational and medicinal purposes, often in its natural form or as extracts to induce relaxation and euphoria.
• The legalization of recreational cannabis in 24 U.S. states has led to increased use and a widespread perception of its safety.
• The impact of cannabinoid use on perioperative opioid requirements remains unclear.
• This study included 157 patients who underwent ankle surgery at John H. Stroger, Jr. Hospital between 2021 and 2023 to investigate this relationship.