•Knee arthroplasty, including total knee arthroplasty (TKA), is an

effective surgical procedure, and ~800,000 procedures are

performed in the United States each year.

•Despite successful surgeries, ~10-20% of patients continue to

experience persistent postoperative pain (i.e., pain more than 3

months after surgery or past the time of normal tissue healing).

•Disabling pain may lead to delayed or reduced functional recovery

and poor quality of life unless it is effectively treated [1].

Study Goal: Characterize responses to 60-day percutaneous

PNS in a post-market, institutional review board (IRB)-approved,

prospectively registered (NCT04341948), multicenter, double-

blind, placebo-controlled, randomized trial [2].

Recently published results found that percutaneous PNS

significantly reduced persistent postoperative pain at the end of

treatment and improved function compared to sham (placebo)

following TKA. The present work reports pain relief and

functional improvement in the treatment group up to 12 months

from the start of treatment.