Peripheral nerve stimulation for treatment of CRPS II in the setting of Ataxia-Telangiectasia.

 

• Ataxia-Telangiectasia (A-T) is a rare autosomal recessive disorder defined by a mutation in the ATM gene that results in defective DNA repair1.

• The condition is characterized by cerebellar degeneration, telangiectasias, peripheral neuropathy, immunodeficiency, pulmonary disease including recurrent infections, and increased susceptibility to cancer and radiation toxicity.

• The worldwide prevalence of A-T is estimated to be between 1:40,000 and 1:100,0001.

• Peripheral nerve stimulation is a form of neuromodulation in which electrodes are placed along the course of peripheral nerves to control pain.

• We present a case of a 29-year-old female with newly diagnosed Complex Regional Pain Syndrome (CRPS) of the right foot in the setting of Ataxia-Telangiectasia successfully treated with peripheral nerve stimulation.