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RCOG World Congress 2025
June 23 - 25, 2025 | ExCeL London, UK
EP.0378
"Endosalpingiosis: A Unique Case Highlighting Diagnostic Challenges in Gynecology"
Poster Presenter
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Part of Topic
Endometriosis & uterine disorders
Endosalpingiosis: A Unique Case Highlighting Diagnostic Challenges in Gynaecology
Introduction
Endosalpingiosis is a benign condition defined by the presence of ciliated tubal-type epithelium in ectopic locations, such as the peritoneum, ovaries, or lymph nodes. Unlike endometriosis, endosalpingiosis is non-functional and does not involve haemorrhage or cyclic changes. It is often asymptomatic but may cause nonspecific pelvic pain, infertility, or mimic malignancies. This report presents the case of a 33-year-old woman with chronic pelvic pain who was diagnosed with endosalpingiosis during laparoscopy.
Discussion
Endosalpingiosis is often detected incidentally during imaging or surgery. Its differentiation from malignancy is crucial due to overlapping presentations. Histopathology remains the gold standard for diagnosis. The etiology is unclear but is hypothesized to involve Müllerian metaplasia or implantation of fallopian tube epithelium. Management focuses on symptom relief, as no definitive treatment is required for asymptomatic cases.
Case report
33 years Female, Chief Complaint: chronic pelvic pain for 1 year. Medical History: No significant history of gynaecological disorders. Obstetric History: G2P2 previous two caesarean sections Clinical Findings: Pelvic tenderness on bimanual examination, No palpable masses Diagnostic Workup: 1. Ultrasound: Normal ovaries and uterus evidence of 3 cm haemorrhagic cyst on left ovary. 2. Tumour Markers: CA-125: Normal, CA 19-9: Normal A diagnostic laparoscopy was performed, revealed pictures of extensive endometriosis, gunshot lesions scattered across peritoneum in all lateral abdominal wall and pelvic walls. There were endometriosis lesions anterior to the uterus and extensive adhesion between uterus and bladder. Pouch of Douglas was obliterated with extensive adhesion between bowel and uterus especially on the left side, with left tube and ovary both stuck on the posterior wall of the uterus and lateral pelvic wall. Histopathological Examination: Specimens revealed ciliated columnar epithelium resembling fallopian tube epithelium., No signs of endometriosis or malignancy. Final diagnosis: Endosalpingiosis. Management Gynaecological MDT discussion recommended to continue management as for endometriosis. Counselling regarding the benign nature of the condition and its distinction from malignancy. Regular follow-up for monitoring symptoms.
Conclusion
This case highlights the importance of considering endosalpingiosis in the differential diagnosis of pelvic pain and cystic lesions in women. Early recognition can prevent unnecessary interventions and alleviate patient anxiety about malignancy.
References
Keltz, M. D., Kliman, H. J., Arici, A. M., & Olive, D. L. (1995). Endosalpingiosis found at laparoscopy for chronic pelvic pain. Fertility and Sterility, 64(3), 482–485. https://pubmed.ncbi.nlm.nih.gov/7641898/ •Heinig, J., Gottschalk, I., Cirkel, U., & Diallo, R. (2002). Endosalpingiosis—an underestimated cause of chronic pelvic pain or an accidental finding? A retrospective study of 16 cases. European Journal of Obstetrics & Gynecology and Reproductive Biology, 103(1), 75–78. https://doi.org/10.1016/S0301-2115(02)00020-9 •Yanli, H., Xiajing, L., Tingting, W., & Qiuni, L. (2025). Postoperative diagnosis of uterine florid cystic endosalpingiosis: a case report emphasizing diagnostic challenges and multimodal imaging correlation. Frontiers in Medicine, 12, 1537986. https://www.frontiersin.org/articles/10.3389/fmed.2025.1537986/full •Ong, N. C. S., Maher, P. J., Readman, E., & Gordon, S. (2003). Endosalpingiosis, an unrecognized condition: report and literature review. Gynecological Surgery, 1(1), 1–5. https://gynecolsurg.springeropen.com/articles/10.1007/s10397-003-0001-0 •Clement, P. B., & Young, R. H. (1999). Florid cystic endosalpingiosis with tumor-like manifestations: a report of four cases. The American Journal of Surgical Pathology, 23(2), 166–175. https://doi.org/10.1097/00000478 199902000-00005
