457 posters, 2 videos, 2 audios, 8 topics, 45 sessions, 401 authors, 265 institutions
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49th Annual Regional Anesthesiology and Acute Pain Medicine Meeting
March 21-23, 2024 | The Hilton Bayfront San Diego | San Diego, California

5102
NEURAXIAL PLACEMENT IN PATIENTS WITH CHIARI I MALFORMATION: A CASE SERIES
Poster Presenter
Authors
Part of Topic
Scientific Abstracts > Case Series
Background
Chiari malformation type 1 (CM-I), is defined as a congenital
Results
Nine patients ranging from ages 22-44 years old (mean age of 33)
herniation of the cerebellar tonsils caudally through the foramen magnum with displacement of the pons and medulla.1 Increased brain turgor due to the malformation may occur, which can interfere with cerebrospinal fluid (CSF) absorption and lead to increased intracranial pressure.2 This can be especially concerning in pregnant patients undergoing labor, where increases in intracranial pressure during labor could potentially result in tonsillar herniation.3 Because of these concerns, administering an epidural can be risky due to possible rupture of the dura and subsequent herniation in CM- 1 patients.4 We present a case series on patients with Chiari malformation undergoing neuraxial anesthesia
Methods
Following the IRB approval to assemble this case series, electronic record databases were used to identify female patients under the age of 50 with Chiari I malformation who had been admitted to the UTMB hospital system. Patients who had delivered, vaginally or via C-section, and had undergone neuraxial analgesia were included in the study. Data on the patients’ age, mode of delivery, type of analgesia, types of anesthetic medications used for analgesia, neurologic symptoms, and other symptoms/complications were collected.
Demographic Data
Results
were included in this case series. Data set included eight Caucasian/White patients and one African American/Black patient. The most common symptoms experienced by these patients were headaches. One patient experienced syncope and sciatica along with their headaches. Another patient experienced headaches and seizures. A third patient experienced visual disturbances, nausea, and vomiting as well. Six out of seven patients tolerated epidural anesthesia. The seventh patient received pudendal nerve blocks and received intravenous opioids for analgesia.
Conclusion
This case series supports that patients with Chiari I malformation can successfully tolerate and undergo neuraxial analgesia for labor but may be more likely to experience neurologic symptoms. In the current case series, patients experienced tolerable symptoms such nausea, vomiting, headaches, and sciatica. One of the patients experienced seizures after placement, but this could not be directly attributed to the epidural itself. However, future studies could aid in determining other forms of management to further prevent neurologic symptoms in this patient population when undergoing neuraxial analgesia.
References
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Gruffi TR, Peralta FM, Thakkar MS, et al. Anesthetic management of parturients with Arnold Chiari malformation-I: a multicenter retrospective study. Int J Obstet Anesth. 2019;37:52-56. doi:10.1016/j.ijoa.2018.10.002
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Waters, Janet F. R., et al. “Management of Anesthesia and Delivery in Women With Chiari I Malformations.” Obstetrics & Gynecology, vol. 132, no. 5, by The American College of Obstetricians and Gynecologists. Published by Wolters Kluwer Health, Inc. All rights reserved, Oct. 2018, pp. 1180–84, doi:10.1097/AOG.0000000000002943.
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Roper JC, Al Wattar BH, Silva AHD, Samarasekera S, Flint G, Pirie AM. Management and birth outcomes of pregnant women with Chiari malformations: A 14 years retrospective case series. Eur J Obstet Gynecol Reprod Biol. 2018;230:1-5. doi:10.1016/j.ejogrb.2018.09.006
Ghaly RF, Tverdohleb T, Candido KD, Knezevic NN. Management of parturients in active labor with Arnold Chiari malformation, tonsillar herniation, and syringomyelia. Surg Neurol Int. 2017;8:10. Published 2017 Jan 19. doi:10.4103/2152-7806.198737
