The AAPS 102nd Annual Meeting

Association Between Genital Reconstruction Surgery and Psychiatric Co-Morbidities in Individuals with Gender Dysphoria

Kassra Garoosi, BS1, YooJin Yoon, BS1 , Elijah Hale, BS1, Riley Kahan, MS1, Nargis Kalia, MPH2, David Mathes, MD2, Ty Higuchi, MD, PhD, Christodoulos Kaoutzanis, MD2

1 University of Colorado School of Medicine, Aurora, CO

2 Department of Plastic and Reconstructive Surgery, University of Colorado Anschutz Medical Center, Aurora, CO

3 Department of Urology, University of Colorado Anschutz Medical Center, Aurora, CO

Background

•Limited data exists regarding the prevalence of psychiatric co-morbidities in patient with gender dysphoria (GD) who have undergone genital reconstruction for genital reconstruction surgery (GRS)

Objective

•This study aimed to investigate rates of psychiatric co-morbidities in patients with GD who have undergone GRS

Methodology

•We conducted a cross-sectional analysis using TriNetX, a healthcare database with >250 million patients

•Using CPT and ICD-10 codes, we identified and compared psychiatric co-morbidity rates in two cohorts:

•1) patients with GD without GRS

•2) patients with GD with GRS. Patients were matched according to age, biological sex, race/ethnicity, and common health co-morbidities.

Results

•We identified 4,061 patients with a history of GD with GRS and 100,097 patients with a history of GD without GRS

•At one-year post-surgery and relative to GD without GRS, the GD with GRS cohort had significantly lower rates of depression, anxiety, substance abuse, and suicidality

•At five years post-surgery, the GD with GRGA had sustained reduced rates of the psychiatric co-morbidities, as well as PTSD

The AAPS 102nd Annual Meeting

Gender Affirming Surgery And Reduced Rates Of Psychiatric Co-morbidities In Patients With Gender Dysphoria

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