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Alzheimer's Association International Conference 2026
July 12-15, 2026 | London, United Kingdom, and Online
13219
From First Visit to Disclosure: How Confirmatory Blood-Based Biomarkers Are Changing Diagnostic Timing in Alzheimer’s Disease
Poster Presenter
Authors
Kimberly Petro, Alison B. Allen, Ryan S. Drake, James E. Galvin, Mario G. Del Valle, Leah Zullig, Douglas Galasko, Soeren Mattke, Michelle M. Mielke, Marwan Noel Sabbagh, Laura L. Schott, Nicholas J. Giordano, Courtney Adams, Feride Frech, Daryl Rhys Jones
Affiliations
Barrow Neurological Institute, Phoenix, AZ, USA, Eisai Inc., Nutley, NJ, USA, Roaring Fork Neurology, Basalt, CO, USA, NeuroCare Center, Inc., Canton, OH, USA, University of Miami Miller School of Medicine, Miami, FL, USA, Duke University School of Medicine, Durham, NC, USA, University of California San Diego, San Diego, CA, USA, University of Southern California, Los Angeles, CA, USA, Wake Forest University School of Medicine, Winston Salem, NC, USA, Premier Applied Sciences, Premier Inc., Charlotte, NC, USA
Part of Topic
Virtual
Summary:
Prospective, multi-site observational study evaluating real-world use of blood-based biomarkers (BBMs) and examined their impact on diagnostic pathways and timelines. BBMs were widely used as confirmatory tools for amyloid pathology, were associated with shorter times from cognitive assessment to result disclosure than PET imaging, and supported earlier-stage Alzheimer's disease diagnosis in routine clinical practice.
Keywords:
Alzheimer's disease (AD) Blood-based biomarkers (BBMs); Amyloid pathology; p-tau217; Aβ42/40; Biomarker testing; Diagnostic pathway; Real-world evidence (RWE); Observational study; Mild cognitive impairment (MCI); Early diagnosis; Diagnostic timelines; Amyloid PET; Confirmatory testing; Clinical workflow; Biomarker utilization.
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