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RCOG World Congress 2025

June 23 - 25, 2025 | ExCeL London, UK

EP.0823

Recurrent Ovarian Germ Cell Tumour during Pregnancy: Case Report Highlighting Management Challenges

Part of Topic

Gynaecological oncology

RECURRENT OVARIAN GERM CELL TUMOUR DURING PREGNANCY: CASE REPORT HIGHLIGHTING MANAGEMENT CHALLENGES

BACKGROUND This case highlights the management of germ cell tumor recurrence during pregnancy. > It emphasizes the complexities of managing cancer during pregnancy, showcases a positive pregnancy outcome, and explores treatment decisions that balance maternal and fetal health.

CASE REPORT 30-year-old woman diagnosed with stage 3A2 yolk sac tumor in 2022. Initial Treatment: Left oophorectomy + BEP chemotherapy. Post-treatment imaging normal. Pregnancy: Conceived post-treatment; no complications until 28 weeks. Recurrence: Purple nodule at laparotomy scar; biopsy confirmed recurrence. Delivery: Caesarean section at 37+1 weeks; tumor excised during delivery. Postpartum Imaging: Solid lesions confirmed recurrence; referred to oncology.

DISCUSSION Individualized Care Plans: Multidisciplinary approach is essential in balancing risks. Timing of Imaging: Postponed CT to avoid fetal exposure; scanned postpartum. Surveillance & Monitoring: Clinical vigilance and patient symptom reporting key. Combined Delivery and Excision: Surgical planning optimized to manage both maternal and fetal health.

Conclusion: - Recurrent germ cell tumors can be managed during pregnancy.- Successful outcomes rely on careful monitoring and multidisciplinary care.- Clinical decisions must prioritize maternal-fetal balance and individualized timing.

KEY LEARNING POINTS ✅ Recurrent tumors during pregnancy can have favorable outcomes ✅ Diagnostic timing should prioritize fetal safety ✅ Surgical and oncological plans must adapt to pregnancy ✅ Multidisciplinary input

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