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RCOG World Congress 2025

June 23 - 25, 2025 | ExCeL London, UK

EP.1947

Increasing RSV vaccine uptake amongst pregnant women: a Quality Improvement Project.

Part of Topic

Quality improvement

Background 

RSV infection is the leading cause of infant hospitalisations worldwide. Infants under 6 months of age are at high risk of severe infections such as bronchiolitis and pneumonia. Globally, approximately 50,000 RSV-attributable deaths occur each year in infants under 6 months of age. Maternal immunisation offers an effective strategy to reduce infant disease severity in this population. As of September 1st, 2024, updated guidelines in the United Kingdom advise that all pregnant women from 28 weeks' gestationshould receive the RSV vaccine. However, due to the recent nature of this policy change, awareness remains limited amongst many expectant mothers and clinicians.Pregnant women are therefore at risk of not receiving the vaccine. Due to the updated guidance and the seasonal peak of RSV activity during the winter months, it is essential to increase public awareness and promote timely vaccination uptake

 

Aim 

To increase RSV vaccine uptake in eligible pregnant women registered at a South London GP practice by 10% within four months.

 

Method 

An Egton Medical Information Systems (EMIS) search was run to identify selected participants within the GP practice who were pregnant and eligible for the RSV vaccine but had not received it. This revealed a cohort of 150 patients. Three Plan-Do-Study-Act (PDSA) cycles weresubsequently conducted between October 2024 and January 2025:

 i) a text-message reminder,

ii) posters displayed in the practice, 

iii) telephone calls to patients.

 

Throughout the PDSA cycles, data on the number of patients vaccinated was documented. 

Patient confidentiality and autonomy were carefully considered, and the security of patient information was maintained throughout the project.


Results 

•RSV vaccine uptake increased from 9% to 25%.
•Quality and Outcomes Framework (QOF) notifications about the RSV vaccine were added into the GP EMIS software as pop-up reminders.

 
Discussion and Conclusion 
 
The clinical implications of this are significant; the RSV vaccine could prevent 5,000 hospitalisations and 15,000 emergency department attendances for infants nationally. At a time when awareness of recent guideline changes remains low, thisQuality Improvement Project hasinitiated appropriate changes in a South London GP practice to support maternal and infant health. By informing patients in a primary care setting, the project allows for wider community outreach and highlights the importance and future need for increasing patient education, awareness, and engagement. 


Acknowledgements 

We would like to thank our supervisor, Dr Laura Bottwood, and our lecturers, Dr Niki Jakeways and Mr Martin Sands, for their continued support throughout this project. 

 

This project was completed as part of the Primary Care intercalated degree at King's College London. 


References 

Hodgson, D., Wilkins, N., van Leeuwen, E., Watson, C.H., Crofts, J., Flasche, S., Jit, M. and Atkins, K.E. (2024). Protecting infants against RSV disease: an impact and cost-effectiveness comparison of long-acting monoclonal antibodies and maternal vaccination. The Lancet Regional Health - Europe, [online] p.100829. doi:https://doi.org/10.1016/j.lanepe.2023.100829.

Li, Y., Wang, X., Blau, D.M., Caballero, M.T., Feikin, D.R., Gill, C.J., Madhi, S.A., Omer, S.B., Simões, E.A.F., Campbell, H., Pariente, A.B., Bardach, D., Bassat, Q., Casalegno, J.-S., Chakhunashvili, G., Crawford, N., Danilenko, D., Do, L.A.H., Echavarria, M. and Gentile, A. (2022). Global, regional, and national disease burden estimates of acute lower respiratory infections due to respiratory syncytial virus in children younger than 5 years in 2019: a systematic analysis. Lancet (London, England), [online] 399(10340), pp.2047–2064. doi:https://doi.org/10.1016/S0140-6736(22)00478-0.

UK, Gov.UK. (2024). RSV vaccination of pregnant women for infant protection: information for healthcare practitioners. [online] GOV.UK. Available at: https://www.gov.uk/government/publications/respiratory-syncytial-virus-rsv-programme-information-for-healthcare-professionals/rsv-vaccination-of-pregnant-women-for-infant-protection-information-for-healthcare-practitioners.

WHO (2025). Respiratory syncytial virus (RSV). [online] Who.int. Available at: https://www.who.int/news-room/fact-sheets/detail/respiratory-syncytial-virus-(rsv).


 

 

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