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RCOG World Congress 2025

June 23 - 25, 2025 | ExCeL London, UK

EP.1887

Audit on Implementation of PLGF Testing in District General Hospital in UK

Part of Topic

Quality improvement

Clinicalaudit : Evaluation of implementation and compliance of placentalgrowthfactor(PIGF) testing in a District General Hospital in UK: NICEDG23

Placental Growth Factor (PLGF) testing is recommended by NICE (DG23) as a diagnostic aid for women presenting with suspected preterm pre-eclampsia between 20+0 and 34+6-weeks gestation.

This audit was undertaken with the aim to:

·Reduce unnecessary hospital admissions by identifying women at low risk
·Minimize inappropriate repeat testing and address documentation gaps
 

Over a period of 16 months all women who were high risk for preeclampsia underwent PLGF testing at QEH.

 Patient notes were reviewed retrospectively to audit current practice against NICE DG 23

 

1. 117 PlGF tests were performed in  QEH out of 150 high risk women for preeclampsia making compliance 78%.

2.14 women PLGF<12, 36 had PLGF between 12-100 and 67 had PLGF >100 who were discharged back to routine care .

3.12 overnight admissions were avoided .

4. 90% of results of PLGF and PET bloods were available in 24 hours.

5. 17 women were tested more than once.

6.80% had clear documentation and appropriate management plans.

The audit revealed significant gaps in  implementation of PlGF testing when compared to NICE standards.

71% of women with PLGF<12 had an adverse pregnancy outcome suggesting PLGF is predicting these consequences.

Overnight hospital stays were avoided in many cases .

Moving forward, improving team education, integrating PLGF testing into existing workflow, and enhancing documentation practices are crucial to optimizing the use of PlGF testing.

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