Acute Generalized Exanthematous Pustulosis in Pregnancy and Postnatally:Rare  Dermatologic Emergency. Case Report And Review of Literature (2020–2025)

Objectives

Acute Generalised Exanthematous Pustulosis (AGEP) is a rare dermatological condition with an incidence of 1–5 cases per million population per year. It is even less common in the pregnant and postpartum population. We performed a literature review of cases reported in the past five years among pregnant and postpartum women and found only a limited number of reports1-4. This case aims to raise awareness of AGEP in obstetric care and promote timely recognition and multidisciplinary management.

Case Presentation

A 34-year-old previously healthy woman underwent an emergency lower segment Caesarean section (LSCS) for obstructed labour. The postoperative course was initially uncomplicated, and she was discharged on day one.

Four days later, she presented to the Accident & Emergency (A&E) department with wound discharge and fever. She was commenced on empirical antibiotics as per the sepsis pathway, on clindamycin and metronidazole, due to penicillin allergy, Upon transfer to maternity triage, different antibiotic was given according to maternity guidelines.

Within 24 hours of antibiotic initiation, the patient developed a widespread erythematous, maculopapular rash starting in the groin and spreading to the trunk, limbs, and face, with associated itching and tenderness. Sheets of pustules emerged