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6th Commonwealth Chemistry Posters

United Kingdom | 1 - 2 October 2025

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P133

A Promising Strategy for Ocular Inflammation: Nanoscale Lipid-Methylprednisolone Conjugates for Targeted Retinal Pigment Epithelium Therapy

Part of Topic

Good Health and Wellbeing (SDG 3)

We have designed nanoscale lipid methylprednisolone conjugates, physicochemically characterized and biologically evaluated.

Size, PdI , Zeta potential and morphology of NPs

%Encapsulation Efficiency

Release Study

Intracellular Trafacking of NPs

Cytotoxicity Assay

qPCR analysis using primers;

Pro-inflammatory

Pain 

Anti-Inflammatory markers

Overall, these findings suggest that NLMCs represent a promising strategy for the targeted delivery of anti-inflammatory agents to the retina. This approach could lead to improved therapeutic outcomes with reduced systemic side effects for inflammatory and pain-related conditions affecting the eye.

 

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