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206 posters, 13 topics, 5 sessions, 713 authors, 293 institutions

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AAPS 104th Annual Meeting

May 2-5, 2026 | Lihue, HI

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PC4

Surgical Outcomes Of Patients Receiving GLP-1 Receptor Agonists Undergoing Breast Reduction Surgery: A Propensity Score-matching Analysis

Part of Topic

Aesthetic Breast/Body Contouring

As GLP-1 receptor agonists (semaglutide, tirzepatide) become increasingly common in patients seeking elective plastic surgery, their impact on wound healing remains poorly characterized. Using TriNetX and 1:1 propensity score matching on 24 covariates, we compared 30-, 90-, 180-, and 365-day postoperative outcomes in breast reduction patients with and without prior GLP-1 use. GLP-1 therapy was not associated with increased major complications but was linked to higher post-procedural wound care utilization and lower fat necrosis at one year.

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