171 posters, 10 topics, 5 sessions, 690 authors, 211 institutions

American Association of Plastic Surgeons Meeting 2022

April 9 - 12 | San Diego, California

P58

Risk Of Post Mastectomy Lymphedema In Autologous Breast Reconstruction: A Multi-center 10-year Analysis Of 9,660 Patients Stratified By Flap-type And Timing Of Reconstruction

Preview of Risk Of Post Mastectomy Lymphedema In Autologous Breast Reconstruction: A Multi-center 10-year Analysis Of 9,660 Patients Stratified By Flap-type And Timing Of Reconstruction

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Poster Presenter

Devinder Singh

Authors

Benjamin Slavin, Susan Taghioff, Shefali Mehra, Kyle Xu, Juan Mella-Catinchi, Tripp Holton, Devinder Singh

Affiliations

University of Miami Miller School of Medicine, Division of Plastic & Reconstructive Surgery, Miami, FL, Anne Arundel Medical Center, Luminis Health Research Institute, Annapolis, MD

Part of Topic

Breast Reconstruction

Risk of Post-Mastectomy Lymphedema in Autologous Breast Reconstruction: A Multicenter 10-Year Analysis of 9,660 Patients Stratified By Flap Type and Timing of Reconstruction

Introduction

•Post-mastectomy, over 20% of women experience lymphedema1,2

•Previous studies suggest a possible protective effect of breast reconstruction against lymphedema development.

•This study aims to temporally analyze post-mastectomy lymphedema in autologous breast reconstruction by flap type and implant-basedreconstruction (IBR) using a continuously-updated, federated electronic medical record network

Figure 1: Forest Plot of Risk Ratios with 95% Confidence Intervals of Lymphedema Risk at 2, 5, and 10 Years Post-Mastectomy, Significant (p<0.05) findings are indicated by an asterisk*, Recon = Reconstruction, MA = Mastectomy, (I) = Immediate Reconstruction, (0d-1Y) = Reconstruction performed immediately-1 year post-mastectomy, (D2d-6M) = Delayed Reconstruction performed 2 days-6 months after Mastectomy, (D6M-1Y) = Delayed Reconstruction performed 6 months-1 year after Mastectomy, (D2d-1Y) = Delayed Reconstruction performed 2 days-1 year after Mastectomy, Lat = Latissimus flap, DIEP = Deep Inferior Epigastric Perforator flap, Tram = Transverse Rectus Abdominus Muscle Flap

Conclusion

•In autologous breast reconstruction, delayed DIEP appears to be most protective against post-mastectomy lymphedema

•Limitations include this study’s retrospective nature and reliance on medical coding.

•Future prospective studies are warranted to confirm whether autologous breast reconstruction, and specifically delayed DIEPs, may be protective against post-mastectomy lymphedema.