171 posters, 10 topics, 5 sessions, 690 authors, 211 institutions

American Association of Plastic Surgeons Meeting 2022

April 9 - 12 | San Diego, California

P43

Acellular Dermal Matrix And Prepectoral Two-stage Breast Reconstruction: A Cohort Analysis Of Alloderm, FlexHD And SurgiMend

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Poster Presenter

Jacqueline Chu

Authors

Jacqueline Chu, Kathryn Haglich, Robyn Rubenstein, Cayla McKernan, Tajah Bell, Richard Poulton, Carrie Stern, Joseph Disa, Michelle Coriddi, Joseph Dayan, Robert Allen, Jr., Babak Mehrara, Evan Matros, Jonas Nelson

Affiliations

Memorial Sloan Kettering Cancer Center, Memorial Sloan Kettering Cancer

Part of Topic

Breast Reconstruction

Purpose

•To determine the impact of acellular dermal matrix (ADM) type on early complications after prepectoral breast reconstruction with tissue expanders.

Background

•ADM is frequently used in prepectoral breast reconstruction.

•ADMs have differences in source and processing methods, which may impact clinical outcomes.

•Few studies have examined role of ADM type on complications in prepectoral reconstruction.

Methods

•Retrospective review of two-stage prepectoral breast reconstruction with ADM patients at Memorial Sloan Kettering Cancer Center from 1/2018 to 12/2021.

•Primary outcome: Tissue expander loss

•Secondary outcomes: Seroma, mastectomy skin flap necrosis, hematoma, TE exposure, TE malposition/rotation, overall complications

Results

•726 patients (Alloderm: 115, SurgiMend: 554, FlexHD: 57)

•1054 TEs (Alloderm: 194, SurgiMend: 767, FlexHD: 93)

•Cohorts were similar in terms of age, race, comorbidities, radiation, chemotherapy, laterality, and axillary lymph node dissection

•Cohorts differed in terms of nipple-sparing mastectomy, use of perforated ADM, and ADM size

Conclusion

•ADM type does not impact risk of TE loss or other early complications after prepectoral breast reconstruction

•Surgeons should take into consideration other factors (cost, ease-of-use, long-term outcomes) when choosing ADM type

•Limitations:

•Smaller sample size of FlexHD TEs

•ADMs used during different time points of study period

•Future research:

•Examine long-term outcomes (capsular contracture)

•Prospective study with larger cohort