Second and third-trimester obstetric outcomes amongst patients with congenital uterine anomalies.

Dr Aleksandra Trojak, Miss Nirmala Vaithilingam

Department of Obstetrics and Gynaecology, Queen Alexandra Hospital, Portsmouth, United Kingdom

 

Objectives: 

Congenital uterine anomalies (CUAs) are rare developmental malformations, which are differentiated based on aetiology, affected structures and clinical presentation. Although the exact prevalence remains undefined, the estimate for the general population varies between 3 and 7% and increases up to 24.5 % in patients affected by pregnancy loss and infertility.

CUAs have historically been associated with an increased risk of complications and adverse pregnancy outcomes, including pregnancy loss, pre-term birth, preterm pre-labour rupture of membranes, malpresentations and fetal growth restriction.

Due to scarce evidence, this study aims to evaluate the obstetric outcomes in patients with CUAs in the second and third trimesters of pregnancy. 

 

Design:

13-month, retrospective, single-cohort study of patients with known congenital uterine anomalies.

Subsequent analysis of data obtained from local electronic health record systems (BadgerNet, Epro, Minestrone, ICE, CHIE).

 

Method:

Centre and data source: Pre-term birth clinic at Queen Alexandra Hospital, Portsmouth, United Kingdom

Data collection: June 2023 until July 2024

Population and clinical information: 

Diagnosis, patient’s age, BMI, smoking status, gynaecological and obstetric history, surgical and medical interventions, clinical management, pregnancy and delivery outcomes

Data analysis tools: Microsoft Excel, Microsoft Word

 

Results: as demonstrated on the graphs

 

Conclusions:

This study demonstrates that despite the elevated risks of complications in pregnancy associated with congenital uterine anomalies, with an implementation of appropriate monitoring and timely interventions, term delivery can be successfully achieved.

References: