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RCOG World Congress 2025
June 23 - 25, 2025 | ExCeL London, UK
PP.0086
Risk Factors for Gestational Diabetes Mellitus: An International, Multi-Centre Retrospective Cohort Study
Poster Presenter
Part of Topic
High risk pregnancy
Audio
Objective
Rising global prevalence of gestational diabetes mellitus (GDM)¹
UK NICE: selective GDM screening using OGTT for high-risk women²
FIGO: recommends universal GDM screening³
Multiple GDM risk prediction tools exist, but limited clinical adoption⁴⁻⁷
Primary aim: Identify risk factors for GDM across four countries (see Table 1)
Secondary aim: Assess sensitivity and specificity of NICE criteria for GDM diagnosis
Design
Retrospective cohort study
Secondary analysis of ‘Impact Diabetes Bump2Baby and Me’ clinical trial
Settings: Australia, Ireland, Spain and the UK⁸
Population: Pregnant women from ~12 weeks' gestation to two years postpartum.
GDM: Positive OGTT between 24-28 weeks using The International Association of Diabetes and Pregnancy Study Groups criteria⁹
Limitations
Small sample size
Study population pre-selected as high-risk using the Monash GDM Screening Tool⁷
Differences between study and general populations e.g. age, employment, education
Missing data, despite use of multiple imputation
Clinical trial involved health management interventions
Additional risk factors of GDM currently outside of the NICE guidance
Highlights the need for combined clinical, biochemical, and sociodemographic stratification in GDM screening
Larger study to stratify universal vs selective screening
