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RCOG World Congress 2025

June 23 - 25, 2025 | ExCeL London, UK

PP.0065

Neonatal Outcomes: Impact of Delivery Mode Across Preterm Gestational Ages

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Poster Presenter

Moonsun Bharj

Authors

Moonsun Bharj, Mia Ashley, Yatra Kapatel, Sana Mughal, Janavi Shah, Stamatina Iliodromiti, Steve Thornton

Affiliations

Barts and The London School of Medicine and Dentistry, NHS, Women's Health Research Unit, Queen Mary, University of London, Royal Holloway, University of London

Part of Topic

Hot topics (emerging research/issues) in obstetrics

How Mode of Delivery Impacts Neonatal Outcomes in Preterm Gestations:

A Systematic Review and Meta Analysis

Authors: Moonsun Bharj(1), Mia Ashley(1), Yatra Kapatel(2), Sana Mughal(2), Janavi Shah(3), Stamatina Iliodromiti(1), Steve Thornton(1). Affiliations: 1: Queen Mary, University of London, London, UK. 2: Royal Holloway, University of London, London, UK. 3: NHS, Surrey, UK

Introduction

Preterm Birth (PTB):

oDelivery before 37 weeks gestation

oLeading cause of mortality in under 5s with ~900,000 babies were born preterm in 2020(1).

Problem:

oIncreased risk of morbidity and mortality with decreased gestational age.

oNo clear guidelines on optimal MOD in PTB(2).

AIM:

To determine the most appropriate MOD in extremely preterm infants (<28 weeks), very preterm infants (29-32 weeks), and moderate to late preterm infants (33-37 weeks).

Methods

PICO Framework:

oPopulation: Pregnant women at risk of giving birth preterm.

oIntervention: MOD (CD vs VD).

oComparison: MOD between WHO gestational age categories (GACs).

oOutcomes: Neonatal mortality, APGAR Score <7 at 5 minutes RDS, BPD, ICH, NEC, Hypoxia, NICU stay and potential adverse neurodevelopmental outcomes at follow-up.

Discussion and Conclusions:

oCaesarean section: associated with a reduction in the risk of intracranial haemorrhage in <28 weeks

oCaesarean section: associated with a lower risk of neonatal mortality in <28 weeks with breech presentation

oLimitations: adjustment for maternal and foetal confounders