POSTER ID EP.1178

 

Title

"From Diagnostics to Outcomes: Innovations Shaping Placenta Accreta Spectrum Disorder Management" 

 

Objective 

 

Placenta previa accreta spectrum (PAS) disorders remain among the most challenging obstetric complications due to their high maternal morbidity and mortality risk. Recent advancements in diagnostic modalities, surgical techniques, and adjunctive therapies have significantly transformed the management of PAS, yielding improved maternal and perinatal outcomes. This review critically examines recent innovations and evaluates their clinical efficacy and implementation.

Study Design and Methods
 This systematic review encompasses studies published in peer-reviewed journals over the past decade, focusing on innovations in the management of PAS. A comprehensive search of PubMed, Embase, and Cochrane Library was performed using predefined keywords including "placenta accreta spectrum," "placenta previa," "surgical innovations," and "management strategies." Inclusion criteria required studies to focus on PAS disorders, explicitly detailing methodologies, interventions, and clinical outcomes. Extracted data were stratified into diagnostic advancements, surgical innovations, and adjunctive therapies. Both qualitative and quantitative analyses were employed, with meta-analysis conducted where sufficient homogeneous data were available.

Data Analysis
 Pooled data were analyzed to quantify the impact of innovations on key clinical outcomes such as intraoperative blood loss, transfusion requirements, maternal morbidity, and mortality. A random-effects model was applied to address heterogeneity in study design and patient populations. Subgroup analyses explored differences in outcomes based on geographic and resource settings.

Results
 The review identified substantial advancements in the management of PAS:

Conclusions
 Innovative diagnostic and therapeutic strategies have redefined the management paradigm for PAS, leading to significant reductions in maternal morbidity and mortality. While these advancements represent a major step forward, challenges persist in achieving equitable access, particularly in resource-constrained settings. Future directions include validating emerging AI-based diagnostic tools, refining minimally invasive surgical techniques, and developing cost-effective management protocols. Multicenter, randomized controlled trials are essential to evaluate these innovations further and optimize their global applicability.

This review underscores the critical role of research, innovation, and multidisciplinary collaboration in improving outcomes for patients with PAS and highlights the ongoing need for equitable healthcare delivery worldwide.

 

 

Categories

Hot topics (emerging research/issues) in obstetrics

Authors and affiliations

 

Dr Yasmeen Akhtar Haseeb (Presenting) dryasmeenhaseeb@yahoo.com

Salmaniya Medical Complex Ministry of Health Bahrain, Bahrain, Bahrain

Arabian Gulf University, Manama, Bahrain