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RCOG World Congress 2023

June 12 - 14, 2023 | London, UK

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EP.1319

“Comparison of different routes of hysterectomies in a tertiary care hospital, Pakistan”

Part of Topic

Benign Gynaecology

“Comparison of perioperative outcomes of different routes of hysterectomies - Total Abdominal, Vaginal & Laparoscopic, in a tertiary care hospital in Karachi, Pakistan”

 

Sarah Rehman¹, Munazza Akhtar2.  Mahnoor Niaz¹, Muhammad Mussab Khakwani¹, Saif Ullah Khan¹, Muhammad Bin Hammad¹, Dr Uzma Chishti²

 

¹Medical College, Aga Khan University, Karachi, Pakistan 

²Department of Obstetrics & Gynecology, Aga Khan University, Karachi, Pakistan

 

ABSTRACT

Background: This study was conducted to compare the perioperative findings among women undergoing hysterectomy by Abdominal (TAH), Vaginal (VH) & Laparoscopic (TLH) routes. 

 

Methods: A 5-year cross-sectional survey was conducted at the Aga Khan University Hospital from January 2015–December 2020 to compare perioperative outcomes of the different routes of hysterectomies. Medical record review of 385 patients who underwent hysterectomy for benign conditions were reviewed and analyzed, out of which 195(50.6%) underwent TAH, 96 (24.9%) VH and 94 (24.4%) were operated laparoscopically Patients with uncontrolled medical comorbid, history of 2 or more abdominal surgeries and uterine size of more than 14 weeks were excluded from the study. 

 

Results: revealed significant difference between the mean hospital stay of patients with TAH having the highest mean stay in days. [TAH= 4.8±1.01, VH= 4.4 ±0.7 and TLH=3.9± 0.82 in days; p<0.01] TLH took comparatively significantly longer operating time than TAH (p=0.0005) and VH groups (p=0.004) however, median estimated blood loss was significantly lower in women who underwent TLH as compare to TAH [Median (25th -75th percentile); 100(50-200)] vs. 300(200-500); p <0.01] and VH [100(50-200)] vs. 250[100-400]; p <0.01]. The incidence of post-operative complications was less than 3% and these were observed in women underwent TAH.

 

Conclusions: VH and TLH have lesser complications and hospitalization days as compared to TAH, making these 2 methods superior. Informed decision making by patient and surgeon’s training together can account for choosing the best method of hysterectomy suitable to the patient.

 

 

 

 

 

 

 

Variables

TAH

(n = 195)

VH

(n = 96)

TLH

(n = 94)

P-Value

Age of patient (years)

45.5 ± 7.0*†

57.8 0± 11.77‡

49.2 ± 10.2

0.0005

Comorbid

 

Hypertension

 

64 (32.8%)*†

 

55 (57.3%)

 

44 (46.8%)

 

0.0005

Diabetic Mellitus

37 (19%)*

29 (30%) ‡

15 (16%)

0.010

Mean parity

3.2 ± 3.07*

4.1 ± 1.87‡

3.09 ± 1.63

0.0005

Uterine size (mm)

AP

Transverse

craniocaudal dimension

 

107.0 ± 30.8*†

64.5 ± 26.7*†

74.4 ± 31.3*†

 

74.6 ± 18.2

41.9 ±1 8.2

46.5 ± 13.7

 

81.4 ± 15.4

48.0 ± 12.6

54.4 ± 15.1

 

0.0005

0.0005

0.0005

Preoperative hemoglobin

11.5 ± 1.4*†

12.3 ± 1.3

11.9 ± 1.2

0.0005

Previous abdominal surgeries

0

1-2

3-5

   

    115 (59%)*†

60 (30.8%)

20 (10.3%)

   

    74 (77.1%)

21 (21.9%)

1(1%)

 

        79 (84%)

15 (16%)

0 (0%)

0.0005

 

Uterine prolapse

 

1 (0.5%)

 

86 (90%)

 

1 (1.1%)

-

Uterine fibroids

97 (49.7%)*†

2 (2.1%) ‡

21 (22.3%)

0.0005

Endometrial

hyperplasia

11 (5.6%)*†

0 (0%)

10 (10.6%)

0.005

Endometriosis

29 (14.9%)*†

1 (1%)

6 (6.4%)

0.0005

Adenomyosis

3 (1.5%)

0 (0%)

1 (1.1%)

0.477

Dysfunctional

Uterine bleed

34 (17.4%)*†

4 (4.1%)‡

33 (35.1%)

0.0005

Other

16 (8.2%)

3 (3.1%)‡

11 (11.7%)

0.0005

Results are reported as mean ± SD and n (%)

Multiple comparison:    TAH vs. VH; *p<0.05 TAH vs. TLH: †p<0.01      AV vs. TLH: ‡<0.05

 

 

 

Outcomes

TAH

(n= 195)

VH

(n= 96)

TLH

 (n= 94)

P-Value

Operating time

(In minutes)

137.9 ± 58.1†

 

141.5 ± 52.0‡

 

169.7 ±- 63.1

0.00005

Length of stay in hospital (days)

4.8 ± 1.0*†

4.3 ± 0.7‡

3.9 ± 0.8

0.0005

Post-operative hemoglobin

 

9.9 ± 1.3*†

 

10.4 ± 1.2

 

10.7 ± 1.2

0.0005

Time to pass flatus (hours)

 

45.6 ± 16.9: †

 

44.7 ± 14.6: ‡

 

37.5 ± 14.2

0.001

Time to mobility/out-of-bed activity (hours)

 

29.5 ± 11.6

 

27.2 ± 8.2

 

30.5 ± 10.7

0.120

Complications

 

 

 

 

Urinary tract injury

2 (1.0%)

2 (2.1%)

0 (0%)

0.367

Laparotomy in cases of VH or TLH

-

9 (9.4%)

3 (3.2%)

0.080

Fever

5 (2.6%)

2 (2.1%)

0 (0%)

0.303

Urinary tract infection

2 (1.0%)

1 (1.0%)

0 (0%)

0.614

Wound infection

2 (1.0%)

0 (0%)

0 (0%)

0.376

Venous thromboembolism

0 (0%)

0 (0%)

1 (1.1%)

0.212

Bowel injury

0 (0%)

0 (0%)

0 (0%)

NA

 

 

 

 

 

 

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