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50th Annual Regional Anesthesiology and Acute Pain Medicine Meeting
May 1 - 3, 2025 | Orlando, Florida
6798
THE IMPACT OF PERIPHERAL NERVE BLOCKS ON CHRONIC OPIOID USE AFTER ELECTIVE TOTAL KNEE ARTHROPLASTY IN THE UNITED STATES
Poster Presenter
Authors
Affiliations
Part of Topic
Scientific Abstracts > Regional Anesthesia
Introduction
Peripheral nerve blocks (PNB) increasingly used in TKA
Recent data:
Equivalence between catheter and single-shot PNB in immediate perioperative analgesia
Large observational dataset —elective TKA from 2017 to 2021— to evaluate the impact of PNB utilization on chronic postoperative opioid use
We hypothesized
US Merative Marketscan data (2017-2021):
1) patients receiving PNB versus those that did not
2) single-shot versus continuous catheter infusion PNB
Primary outcomes:
1) “chronic opioid dependence” (>120 pills of opioids prescribed or >10 prescriptions between postoperative day 90-180)
2) “chronic opioid use” (any opioid refill between postoperative day 90-180)
Multivariable models report odds ratios (OR) and 95% confidence intervals (CI)
Results
Incidence of “chronic opioid dependence” was 0.8%, 0.9% and 1.0% without PNB, with single-shot PNB, and continuous PNB
In conclusion, the use of PNBs and the comparison between single-shot and catheter PNBs did not appear to be associated with lower odds of postoperative chronic opioid dependence and/or chronic opioid use.
However, we did observe slightly increased odds of chronic opioid use associated with PNB use which should be explored in future studies.