Prospective randomized trial of efficacy and safety of erector spinae catheter and intercostal nerve cryoablation protocols after pectus surgery: Interim analysis

Suryakumar Narayanasamy1, Charlotte Walter1, Kristie Geisler1, Lili Ding2, Jiwon Lee2, Rebeccah Brown3, Vidya Chidambaran1.

1Department of Anesthesia, 2Division of Biostatistics, 3Division of Surgery, Cincinnati Children's Hospital Medical Center

Background

Cryoablation of the intercostal nerves (INC), is being used increasingly for pain control used in adolescent patients for Nuss procedures.

It is imperative to study the efficacy and safety of INC in randomized controlled trials.

Aims and objectives:

To compare efficacy (functional recovery and clinical pain outcomes) and safety (neurological sequelae) in patients undergoing INC and multimodal ES catheter protocols for pain control after pectus surgery repair.

Methods

12- to 21-years Group ESC vs INC

Outcomes: Time to walk in the hallway and climb stairs, Morphine Milligram Equivalents (MMEs), S-LANSS score: Leeds Assessment of Neuropathic Symptoms and Signs (self-complete)

Results

 This research was funded by AIP grant, Department of Anesthesia, CCHMC

References:

1.Harbaugh, C. M. et al. Journal of Surgical Research 231 (2018): 217-23.

2.Zobel, M. J. et al. Pediatric surgery international 36 (2020): 317-24.

3.Chidambaran, V. et al. Anesth Analg 134 (2022): 881-84.

4. Bennett MI, et al. J Pain. 2005 Mar;6(3):149-58.