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425 posters, 1 videos, 9 audios, 8 topics, 53 sessions, 340 authors, 286 institutions

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22nd Annual Pain Medicine Meeting 2023

November 10 - 11, 2023 | New Orleans Marriott | New Orleans, Louisiana, USA

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4607

PERCUTANEOUS PNS RELIEVES PERSISTENT POSTOPERATIVE PAIN AND IMPROVES FUNCTION AFTER TKA: RESULTS FROM A PLACEBO-CONTROLLED RCT

Poster Presenter

John Gilbert

Authors

John Gilbert

Affiliations

SPR Therapeutics

Part of Topic

Chronic Pain

Percutaneous PNS Relieves Persistent Postoperative Pain and Improves Function after TKA: Results from a Placebo-Controlled RCT
•Total knee arthroplasty (TKA) is an effective surgical procedure, and approximately 800,000 procedures are performed in the United States each year, but ~10-20% of patients continue to experience persistent postoperative pain (i.e., pain >3 months after surgery or past the time of normal tissue healing)
•Postoperative pain may lead to functional limitations and poor quality of life [1]

Study Goal: Characterize responses to 60-day percutaneous PNS in a post-market, institutional review board (IRB)-approved, prospectively registered (NCT04341948), multicenter, double-blind, placebo-controlled, randomized trial.

Non-opioid, non-destructive, non-surgical, minimally invasive, 60-day percutaneous PNS demonstrated: 

•Significant pain relief compared to placebo (sham) stimulation during weeks 5-8.
•Increased walking ability compared to placebo (sham) stimulation, which may be beneficial for encouraging activity and improving functional recovery for TKA patients with decreased postoperative mobility.
•Improved function and quality of life in multiple outcomes compared to placebo (sham) stimulation, including stiffness and physical function.
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