241 posters, 10 topics, 7 sessions, 899 authors, 296 institutions
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The AAPS 103rd Annual Meeting 2025
May 24-27, 2025 | Austin, Texas
P42
Effect Of Marijuana Use On Outcomes In Patients Undergoing Reduction Mammaplasty: A Retrospective Cohort Study
Part of Topic
Outcomes
The Impact of Marijuana Use on Postoperative
Outcomes in Reduction Mammaplasty
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Tetrahydrocannabinol may impact platelet function, inflammation, and wound healing1-2
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Associated with impaired healing, increased pain, and infection in other surgical subspecialties2-4
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Study aim was to evaluate association between marijuana use and complications in reduction mammaplasty
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Single institution retrospective cohort study between 2019 – 2024
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Included participants were >18y of age and had >2w follow up
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Excluded participants who underwent oncologic or revision breast reduction
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Bivariate and multivariable analysis on a “per breast” basis
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2.93 times increased odds of hematoma
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THC reduces platelet aggregation5-7
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Marijuana associated with endothelial dysfunction and vasodilation8-14
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1.99 times increased odds of delayed wound healing
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THC impairs collagen synthesis and angiogenesis15-16
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Cannabis exposure linked to fibroblast dysfunction and altered immune response17-19
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Critical to counsel patients on the potentially negative effects of marijuana use in reduction mammaplasty
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Consider marijuana cessation in the perioperativeperiod