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Alzheimer's Association International Conference 2026
July 12-15, 2026 | London, United Kingdom, and Online

990
Bidirectional Associations Of 24-hour Activity Cycle Behaviors And Cognitive Function Among Older Adults: Is It Reverse Causation?
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•Physical activity (PA), sedentary behavior (SB), and sleep are independently associated with future cognitive decline.
•Some evidence suggests the potential for bidirectional associations.
•However, few studies have examined whether cognitive decline leads to lower levels of PA, higher levels of SB, and worse sleep.
•Here, we examined whether cognitive trajectories are predictive of PA, SB, and sleep in a community-based cohort of older adults.
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