Objective: To examine the effects of gadolinium-based contrast agent (GBCA) on brain conductivity changes and to compare differences in conductivity maps before and after GBCA injection between AD or mild cognitive impairment (MCI) and cognitively normal (CN) participants.

Main findings: 1)White Matter Conductivity Increases as Cognitive Impairment Progresses. 2)Conductivity Heterogeneity Indices Effectively Differentiate MCI and AD from Normal Brains. 3)Linear Patterns in GBCA Leakage Map Vascular Damage