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Alzheimer's Association International Conference 2026
July 12-15, 2026 | London, United Kingdom, and Online
1155
Associations between psychological factors and lifestyle changes for dementia risk
Poster Presenter
Authors
Oriol Perera-Cruz, María Cabello-Toscano, Cristina Solé-Padullés, Rachel Morse, Gabriele Cattaneo, Javier Solana-Sánchez, Álvaro Pascual-Leone, Lídia Vaqué-Alcázar, David Bartrés-Faz
Affiliations
Harvard Medical School, University of Barcelona, Lausanne University Hospital, Guttmann Institute, IRB Sant Pau Hospital
Part of Topic
INTRODUCTION
Recent research shows psychological characteristics influence dementia risk and cognitive decline. A novel person-centered approach aggregates psychological factors into latent profiles of individuals. In the present work, we apply this idea to longitudinal psychological and lifestyle data to:
1. Assess latent profiles stability
2. Assess the relationship between psychological and lifestyle profiles.
METHODS
A total of N = 1379 healthy middle-aged individuals from the Barcelona Brain Health Initiative (BBHI) remotely completed questionnaires for 2 timepoints on psychological data and 5 timepoints on lifestyle data. A Latent Transition Analysis (LTA) was implemented using the LMest() RStudio® package on either psychological or lifestyle variables.
CONCLUSIONS
1.Both psychological and lifestyle profiles show high stability across timepoints, with risk profiles presenting the lowest stability
2.Balanced psychological profiles engage in healthier lifestyles, while risk profiles show higher proportions of unhealthy lifestyle groups and lifestyle changing subjects
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