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Alzheimer's Association International Conference 2026

July 12-15, 2026 | London, United Kingdom, and Online

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9166

Healthy Aging Through The Senior Years (HATS) Cohort: Brain Health Among Older Black Adults In The United States

Poster Presenter

Kerry Sheets

Part of Topic

Healthy Aging Through the Senior Years (HATS) Cohort: Brain health among older Black adults in the United States

#9166

Kerry M. Sheets, MD, MS1,2; David S Knopman, MD3; Jonathan Graff-Radford, MD3; Ronald C Petersen, MD, PhD3; Vemuri Prashanthi, PhD3; Clarence Jones4; Monisha Washington, CHW5; Robbin Frazier2; Anne M Murray, MD, MSc1,2

1Hennepin Healthcare Research Institute, Minneapolis, Minnesota (MN), USA; 2University of Minnesota, Minneapolis, MN; 3Mayo Clinic, Rochester, Mn; 4HueMan Partnership, Minneapolis, MN; 5The Linc, Minneapolis, MN

HATS is a novel longitudinal cohort that is well-positioned to advance understanding of modifiable risk factors for dementia among Black Americans living in the upper Midwest of the United States. Recruitment is ongoing will a focus on enrolling men and participants with a wide range of cognitive function. 

INTRODUCTION 

•Dementia is up to twice as common in older Black Americans compared to older Non-Hispanic White Americans
•Vascular disease is thought to be an important cause of dementia in older Black Americans
•However, the role of modifiable cardiovascular factors has been understudied
•HATS focuses on modifiable cardiovascular and sociodemographic contributions to brain health among older Black Americans

METHODS

Inclusion criteria: Age 55 years or older, Black race, Live in and around Minneapolis, MN

Exclusion criteria: Vision, hearing, or cognitive impairment that limits ability to participate in HATS assessments

Recruitment: Community-based and led by community partners

Visit frequency: In-person study visits every 15-18 months for 5 years

Data collection: Includes neuropsychiatric assessments, informant interviews, 3T brain MRIs, and ADRD blood-based biomarkers

RESULTS

•Community engagement including providing dementia education is a key component of HATS
•The HATS participant appreciation event in September of 2025 was attended by >60 participants and community members

CONCLUSIONS

•HATS will advance understanding of modifiable risk factors for dementia among Black Americans 
•Recruitment is ongoing 
•Focus is on enrolling men and participants with a wide range of cardiovascular risk profiles and cognitive function

Concact: Kerry.sheets@hcmed.org

 

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