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Alzheimer's Association International Conference 2026
July 12-15, 2026 | London, United Kingdom, and Online
6929
Distinctive Sleep Phenotypes In Former Elite Contact-sport Athletes Are Associated With Memory Independent Of Alzheimer's Pathology
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DISTINCTIVE SLEEP PHENOTYPES IN FORMER ELITE CONTACT-SPORT ATHLETES ARE ASSOCIATED WITH MEMORY INDEPENDENT OF ALZHEIMER'S PATHOLOGY
INTRODUCTION
•Sleep disturbances are common in Alzheimer’s disease (AD)1 and often precede cognitive decline.
• Former contact-sport athletes also report poor sleep2 and elevated pTau2173 associated with repetitive head impacts (RHI), yet objective characterisation of sleep in this population remains limited.
•We hypothesised that longitudinal, contactless-monitoring of sleep would identify abnormal sleep profiles in former elite contact-sport athletes (association football and rugby), which would relate to memory performance, potentially via AD-related pathology.
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