Authors: 

Mirella Díaz-Santos, Jim Kelly, Sydney Kilgore, Jae Toyota, Katy Figueroa, Kimberly Cyrus, Ariadna Martinez, Monica Moore, Nancy Osuch, Samantha Shah, Nathalie Vizueta, Kacie Deters, Jennifer Adrissi, Norma Guerra, Krystal Flores, Lourdes Reynolds, Elizabeth Rose Mayeda, Timothy Chang, & Keith Vossel

DREAM-LA Study

Scientific goal: Develop inclusive datasets for predictive models of early AD/ADRD detection.

Implementation challenge: Recruiting historically underrepresented communities into a biomarker-intensive protocol.

Implementation strategy: Embed a sustained, culturally grounded Community Advisory Board.

Early implementation outcomes: Diverse enrollment, participant understanding, adaptive recruitment, and trust-building.

Long-term impact: More representative biomarker datasets that can support equitable endophenotype discovery and predictive modeling for earlier AD/ADRD detection.