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Alzheimer's Association International Conference 2026

July 12-15, 2026 | London, United Kingdom, and Online

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6751

A Multi-phase Methodological Framework For Non-invasive Dementia Pre-diagnosis

Part of Topic

Early detection of dementia at the primary care level remains a persistent challenge, particularly in Latin America, where a substantial proportion of cases remain undiagnosed [1]. Diagnosis frequently occurs at advanced stages, when clinical symptoms are clearly manifested and patients are referred to specialist services [2]. In this context, the development of early diagnostic technologies represents a valuable resource for primary care clinicians, enhancing the detection of subtle and early indicators of dementia.

Methodology:

Phase 1: Affective-Cognitive Couplin. (Emotion During MMSE Procedure)

- Facial expressions were captured via webcam and analyzed using facial emotion recognition software.

- Data Collected: Valence levels aligned with specific MMSE sub-items.

Phase 2: Linguistic Markers (Speech Analysis)

- Procedure: Participants performed structured tasks including picture description and paragraph reading.

-Features Extracted: Lexical richness, speech rate and pause frequency.

Conclusions

  • Technological tools showed potential for assessing different dimensions of dementia-related decline.
  • Technology-driven approaches can support the early identification of cognitive impairment.
  • A multi-phase framework was established to enable pre-diagnostic dementia assessment through validated data acquisition and analytical methods.

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