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Alzheimer's Association International Conference 2026
July 12-15, 2026 | London, United Kingdom, and Online
2107
Towards a neural exposome of India
Poster Presenter
Authors
Leon Aksman, Kirsten Lynch, Yingxu Liu, Emma Nichols, Alden Gross, Lindsay Kobayashi, Miguel Arce Rentería, Pranali Khobragade, Joyita Banerjee, Niranjan Khandelwal, Jinkook Lee
Affiliations
Department of Epidemiology, University of Michigan School of Public Health, Ann Arbor, MI, USA, Mark and Mary Stevens Neuroimaging and Informatics Institute, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA, Center for Economic and Social Research, University of Southern California, Los Angeles, California, USA, Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA, Department of Neurology, College of Physicians and Surgeons, Columbia University, New York, New York, USA, Department of Radiodiagnosis, National Institute of Medical Sciences, Jaipur, Rajasthan, India
Part of Topic
INTRODUCTION
Little is presently known about how modifiable dementia risk factors associate with brain pathologies in India, the world’s most populous country.
OBJECTIVE
Establish a structural MRI based neural exposome of India by associating all 14 Lancet Commission modifiable dementia risk factors with neurodegenerative markers of excess atrophy.
DISCUSSION
Obesity (in the unexpected direction), social isolation, PM2.5 air pollution and poverty may have early influences on neurodegeneration, especially hippocampal atrophy and decreased cortical thickness, among globally established modifiable risks in India.
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