• Communicating Alzheimer’s disease (AD) risk and APOE genotype information with relatives can help family members understand their potential risk and consider available testing or prevention opportunities.

• Prior research on the familial patterns of communication of results has focused on predominantly non-Latino White, highly educated samples.

• This study aims to (1) examine with whom Latino adults shared AD risk and/or APOE genotype information, (2) identify predictors of sharing, and (3) explore motivations and barriers of communicating results with family members.

• We used convergent mixed-methods analysis of English- and Spanish-speaking Latino adults ages 40-64 in northern Manhattan from the IDEAL study.

• Participants were randomized to receive AD risk information based on family history (nondisclosure) or the same information plus APOE genotype (disclosure).

• Survey participants (N=338) reported at 6 weeks and/or 9 months whether they shared their results and with whom.

• Demographic and psychosocial factors were assessed; variables significant in bivariate analyses were included in multivariable logistic regression models.

• Interviewed participants (N=153) completed a 6-week and/or 9-month interview.

• Interview data were analyzed thematically to identify motivations and barriers to communicating results with family members.

• Communication of AD risk was common among family members and shaped by a variety of factors such as receiving genetic test results, being a man, and perceived AD stigma.

• Risk disclosure and genetic counseling should include family-centered, stigma-informed, and language-concordant support to help participants communicate risk information in ways that promote understanding while minimizing distress.