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Alzheimer's Association International Conference 2026
July 12-15, 2026 | London, United Kingdom, and Online
9488
Relationship Of Genetic Variants And Gene Expression Of SLC16A7With Cognitive Decline In Older Adults
Poster Presenter
Authors
John Dou, Kelly Bakulski, Yiyang Wu, Vaibhav Janve, Elizabeth Litkowski, Arturo Rocha, David Bennett, Timothy Hohman, Catherine Kaczorowsk
Affiliations
School of Public Health, University of Michigan, Ann Arbor, Vanderbilt Memory and Alzheimer's Center, Vanderbilt Health, Nashville, Michigan Medicine, University of Michigan, Ann Arbor, Rush Alzheimer’s Disease Center, Rush University Medical Center, Chicago
Part of Topic
Relationship of genetic variants and gene expression of SLC16A7 with cognitive decline in older adults
Health and Retirement Study (HRS)
Religious Orders Study and Rush Memory and Aging Project (ROSMAP)
Suggestive associations of cognitive decline and SLC16A7 variants, some of which previously identified as genetically influencing gene expression in brain
Expression of SLC16A7 in postmortem brain is associated with longitudinal global cognition, and marginally with AD pathology
Genetic associations involving eQTL SNPs, and brain RNA-expression associations both implicate SLC16A7 levels in influencing cognition
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