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Alzheimer's Association International Conference 2026
July 12-15, 2026 | London, United Kingdom, and Online
6623
The Modulating Role Of Sex In The Relationship Between Blood Cholesterol Markers And Neurovascular Pathology
Poster Presenter
Authors
Zoe Tsokolas, Amaryllis Tsiknia, Melissa Petersen, Arthur Toga, Sid O'Bryant, Kristine Yaffe, Kevin King, Matthew Borzage, Meredith Braskie
Affiliations
Mark and Mary Stevens Neuroimaging and Informatics Institute, Keck School of Medicine, University of Southern California, Los Angeles, CA, Institute for Translational Research, University of North Texas Health Science Center, Fort Worth, TX, United States, Weill Institute for Neurosciences, University of California San Francisco, San Francisco, CA, United States, Department of Neuroradiology, Barrow Neurological Institute, Phoenix, AZ, Fetal and Neonatal Institute, Division of Neonatology, Children’s Hospital Los Angeles, Department of Pediatrics, Keck School of Medicine, University of Southern California, Los Angeles, CA; Institute for the Developing Mind, Children’s Hospital Los Angeles, Los Angeles, CA, USA; Department of Psychiatry, Keck School of Medicine, University of Southern California, Los Angeles, CA
Part of Topic
Conclusions:
● Sex moderated the relationship between HDL-c and WMH such that greater HDL-c levels were associated with lower WMH in males only
● Circulating cholesterols differentially associate with WMH, and HDL-c uniquely demonstrates a non-linear relationship with WMH burden
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