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Alzheimer's Association International Conference 2026
July 12-15, 2026 | London, United Kingdom, and Online
1688
Pqtl-driven Bayesian Network Reveals Hierarchical Genetic Architecture In CSF Proteomics
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•Proteomics can capture disease-relevant molecular changes in neurodegeneration.
•Protein quantitative trait loci (pQTLs) provide genetic anchors for interpreting protein regulation.
•Network analysis can reveal coordinated protein changes across biological pathways.
•We built a BioFINDER proteogenomic resource integrating proteomics and genetics.
•We used this resource for pQTL mapping and ongoing genetics-informed network analysis.
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