Title: CogCoach-Health: Protocol For A Digitally Delivered, Low-intensity, Multidomain Dementia Risk Reduction Trial In Adults With SCD And MCI

Authors: Jessica G. Amos1,2, Nicola T. Lautenschlager3, Lidan Zheng1,2, Brenda Gannon4, Sharon Naismith5, Md Hamidul Huque1,2, Dimity Pond6, Genevieve Z. Steiner-Lim7, Kim Delbaere1, Kirsten McCaffery5, Terence W.H. Chong3, Dina LoGiudice3, Viviana Wuthrich8, Karen Charlton6, Ranmalee Eramudugolla1, Kaarin J. Anstey1,2.

Introduction: Modifiable lifestyle and health factors influence dementia risk, and older adults with subjective cognitive decline (SCD) and mild cognitive impairment (MCI) represent a critical population for preventive interventions, given elevated risk1. While multidomain interventions can reduce dementia risk, many are resource-intensive and difficult to scale. Digitally-delivered, less resource-intensive interventions may offer a feasible and scalable approach. The CogCoach-Health intervention was co-designed with stakeholders to provide a structured program with ongoing support for behaviour change, suitable for remote delivery and tailored to older adults with memory concerns.

Aims & Objectives: 

Primary aim: Evaluate the effectiveness of a digitally delivered multidomain intervention (CogCoach-Health), compared to email-based psychoeducation, for reducing the risk of dementia after 12 months (measured by ANU-ADRI2) in people with SCD or MCI.

 Secondary objectives:

• Evaluate CogCoach-Health for change in cognitive functioning‡, MIND diet, physical activity, dementia literacy, cognitive engagement, quality of life and health-related quality of life.
• Evaluate feasibility, adherence, and the efficacy of behaviour change technique components.
• Evaluate the cost-effectiveness of CogCoach-Health compared with active control using healthcare utilisation data obtained through Medicare linkage.