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Alzheimer's Association International Conference 2026
July 12-15, 2026 | London, United Kingdom, and Online

9912
The Association Between Plasma P-tau217, Sleep, And Speech Rate Over Time In Cognitively Unimpaired Older Adults
Poster Presenter
Authors
Phoebe Crumpton, Kristin Basche, Anikka Baker, Bruce P. Hermann, Jessica Caldwell, Ramiro Reyes, Rachael E. Wilson, Nathaniel C. Chin, Barbara B. Bendlin, Henrik Zetterberg, Sterling Johnson, Kimberly Mueller
Affiliations
Communication Sciences and Disorders Department, University of Wisconsin-Madison, Madison, WI, USA, University of Wisconsin-Madison, Madison, WI, USA, University of Wisconsin-Madison, Department of Neurology, Madison, WI, USA, University of Wisconsin-Madison, Wisconsin Alzheimer's Institute, Madison, WI, USA, University of Wisconsin-Madison, School of Medicine and Public Health, Geriatrics and Gerontology, Madison, WI, USA, University of Wisconsin-Madison, Alzheimer's Disease Research Center, Madison, WI, USA, University of Wisconsin-Madison, School of Medicine and Public Health, Madison, WI, USA
Part of Topic
Connected speech analysis is a promising low-cost approach to capture complex cognitive-linguistic functions with minimal burden. In this study, we evaluated whether sleep quality interacts with plasma p-Tau217 status to predict longitudinal change in speaking rate in a cohort enriched for AD risk.
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