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Alzheimer's Association International Conference 2026
July 12-15, 2026 | London, United Kingdom, and Online
10208
Racial And Regional Disparities In Mortality From Alzheimer's And Related Dementias In The United States, 2013-2023
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Racial and Regional Disparities in Alzheimer’s and Related Dementia Mortality in the United States, 2013–2023
Tej Shah1, Niying Li, PhD2, Monica Parker, MD3, Ambar Kulshreshtha, MD, PhD3
1School of Public Health, Emory University, 2College of Pharmacy, University of Georgia, 3School of Medicine, Emory University
Background and Hypothesis
-Alzheimer’s disease and related dementias (ADRD) are among the leading causes of death in the U.S.
-Disparities in ADRD mortality have been observed across racial and regional lines, but findings are inconsistent.
-We aimed to analyze the latest 10-year national trends of disparities in ADRD mortality by race and U.S. census division.
Data and Methods
-Data Source: CDC WONDER database (2013–2023).
-Population: U.S. deaths where ADRD was listed as the underlying cause using ICD-10 codes.
-Measures: Age-adjusted mortality rates (AAMR) were calculated by:
-Race: Black and White
-Census Region
-Dementia Type: Alzheimer’s vs. vascular dementia
-AAMR is reported as deaths per 100,000, age-standardized to the 2000 U.S. population.
Results
-National AAMR for ADRD peaked in 2020 (294/100,000) and declined to 256.1 by 2023.
-New England surpassed East South Central in 2023 with the highest regional AAMR at 331.1 deaths per 100,000.
-White Americans had consistently higher ADRD mortality than Black Americans (267.2 vs. 236.1 in 2023).
-However, Black Americans had higher mortality from vascular dementia across most of the decade.
Limitations
-Cause-of-death misclassification is possible using death certificate data.
-Lack of individual-level data (e.g., socioeconomic status, healthcare access, comorbidities) limits interpretation.
-Pandemic-related mortality fluctuations in 2020–2021 may influence results.
Conclusions
-Over the last decade, White Americans have had higher ADRD mortality, though vascular dementia remains more fatal among Black Americans.
-Regionally, the South was historically most affected, but New England now reports the highest mortality.
-These trends may reflect underlying vascular risk, population aging, and diagnostic differences, not just healthcare availability.
-Continued monitoring and region-specific public health responses are needed to address the evolving dementia burden.
References
Interested in the overall ADRD data & vascular dementia mortality trends by race?
Scan the QR code below to view the references, dataset and graphs.
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