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2026 SOAP Annual Meeting

April 29 - May 3, 2026 | Montreal, Quebec Canada

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2341894

Navigating the Nuances: A Case of Post Dural Puncture Headache Followed by Massive Cerebral Venous Sinus Thrombosis

Part of Topic

PDPH: Management and Morbidity

Background

Cerebral venous sinus thrombosis (CVST) is a rare and life-threatening complication following delivery 

Early stages of CVST may mimic PDPH

Unintentional dural puncture (UDP) increases the risk of CVST

We present a case of UDP with acute PDPH followed by subacute CVST

 

Case

PPD 0- Unintentional dural puncture

PPD 1- Positional headache (HA) à PDPH

Epidural blood patch performed. HA resolution

PPD 9- Presented to ED with recurring HA, desired conservative management, discharged with Fiorcet

PPD 11- Returned to ED with worsening HA, mental status changes, and new neurologic deficits

CT venogram- extensive CVST

Therapeutic anticoagulation and neuro ICU

PPD 25- Discharged to inpatient rehab with near-baseline return of function

 

Teaching Points

Heightened vigilance in obstetric patients with unintentional dural puncture

Early neuroimaging in atypical/refractory cases

Dural puncture alters CSF dynamics

Cerebral venous dilation and stasis of CSF flow

Post Dural Puncture Headache

Cerebral Venous Sinus Thrombosis

Classic positional component

Absent or atypical positional component

24-72 hours onset

Days to weeks onset

Focal deficits rare

Commonly seizures, focal deficits, AMS, papilledema

Conservative management à epidural blood patch

Therapeutic anticoagulation

 

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