Assessment of Anti-Oxidant Capacity of Saliva and Oral Health in Cerebral Palsied Children
Cerebral palsy (CP) is disorder of movement and posture due to a defect or lesion of the immature and permanent damage of the brain. This condition is the most widely recognized reason for extreme physical inability in childhood (Rosenbaum et al., 2007)
Antioxidants (AO) have been shown to neutralize free radicals contributing to oxidative stress and inflammation as a part of internal defense mechanism found in all biological species and it works as a protective agent against any cell damage (Pham-Huy et al., 2008) (Tulunoglu et al., 2006) .
In CP children, they found an inverse relationship between dental caries and Total Antioxidant Capacity (TAC) . (Subramaniam et al., 2014).
Aims & Objectives:
Assessment of total anti-oxidant capacity level in Cerebral Palsied children and its relation to oral health status.
Study area: The present study will be conducted in Sultan Bin Abdulaziz Humanitarian city for children with CP for test group.
Study population : the study population implicated young patients aged between 3-12 years of age , this study conducted the time frame of 4 months .
Sample size : 24 children for each group .
Inclusion criteria : Children Diagnosed with CP (test group and Healthy Children (control group ) age between 3-12 years of age .
Exclusion criteria : Any patient diagnosed with any other disease or syndrome , age range not within 3-12 years of age .
Study tools : Disposable OD kit , pipe for collected the saliva .
Children with CP showed high carious rate compared to the normal children , mostly because of having the bad oral hygiene . excess use of Antioxidants to neutralize the free radicals released due to oxidative stress in CP patient . SO ,slivary antioxidant levels in CP patients was found to be low.
Though not significant , TAC of saliva showed an inverse relation with dental caries in CP patients .