Skin Microbiome and Acne Vulgaris: Staphylococcus, A New Actor in Acne
Acne is a chronic inflammatory disease targeting the pilosebaceous follicle. Propionibacterium acnes (P. acnes), the sebaceous gland and follicular keratinocytes play a role in the development of acne. Together they induce inflammation in the follicle by activating the innate immunity. For several years, the role of Staphylococcus, another bacterium genus, has been discussed in the development of acne. However, to date its role has never been skin and acne lesions (comedone and papulo-pustular lesions) and to determine changes after applying either erythromycin 4% or a dermocosmetic containing lipohydroxy acid, salicylic acid, linoleic acid, niacinamide, piroctone-olamine, a ceramide and Thermal Spring Water for 28 days.