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119 posters, 6 topics, 524 authors, 243 institutions

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RCR Global AI Conference 2026

29-30 June, 2026 | QEII Centre, Westminster

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151

Integrating an Institutional Large Language Model into Magnetic Resonance Imaging Requests

Part of Topic

Transforming practice and leadership: pilot or test data on implementation of AI into clinical practice, clinical feedback or patient perspectives

Background

Objectives

Initial Insights Into a Secure Large Language Model for MRI Examination Requests: A Retrospective Study

James Thomas Patrick Decourcy Hallinan¹˒², MBChB; Naomi Wenxin Leow³, BComp, MComp; Yi Xian Low¹, MBBS; Aric Lee¹, MBBS; Wilson Ong¹, MBBS; Matthew Ding Zhou Chan¹, BmedSc, MD; Gordan Toh Cheong Zheng⁵, Diploma in Biomedical Science; Ganakirthana Kalpenya Devi¹, MbBchBao; Stephanie Shengjie He¹, MBBS; Daniel De-Liang Loh¹, MBBS, MRCS; Desmond Shi Wei Lim¹, MBBS; Xi Zhen Low¹, MBBS; Mei Chin Lim¹, MBBS; Clement Yong¹, MBBS; Weizhong Jonathan Sng¹, MBBS; Ee Chin Teo¹, MMRT; Jiong Hao Tan⁴, MBBS, MMed, MRCS; Naresh Kumar⁴, MBBS, MS, DNB, DM; Andrew Makmur¹˒³, BmedSc, MBBS, MMed; Yonghan Ting¹, MBBS

¹ Dept. of Diagnostic Imaging, NUH, Singapore

² Dept. of Diagnostic Radiology, YLL School of Medicine, NUS, Singapore

³ AI Office, NUHS, Singapore

⁴ National University Spine Institute, NUH, Singapore

⁵ Republic Polytechnic, Singapore

For all MRI subspecialty modalities (Musculoskeletal, Neuroradiology, body):

  1. Does sLLM augmentation improve clinical information quality of MRI examination requests?
  2. Can sLLM match radiologist-level MRI protocol accuracy?

Main Findings

Discussion

Materials and Methods

Limitations

Conclusion

Rule-Based Protocol Assignment

Maps extracted elements → MRI region, coverage & contrast using institutional protocol library

Institutional sLLM based on Claude 3.5 · Temp 0

RI-RADS graded [1] · Retrospective

Sept 2023 – Jul 2024

n= 608 MRIs · 528 patients

Grade Description Information included in the requisition
RI-RADS A Adequate All key categories of information included.
RI-RADS B Barely adequate All key categories of information included, some clinical findings missing.
RI-RADS C Considerably limited Two categories of information included.
RI-RADS D Deficient One or no category of information included.
 
  • Incomplete Magnetic Resonance Imaging (MRI) requests lead to suboptimal protocols, repeat studies & reduced accuracy.
  • LLMs can interpret clinical text at scale, but privacy constraints limit direct clinical use
  • Institutional sLLMs operate behind firewalls, protecting patient data while enabling augmentation
  • sLLM upgraded MER quality across all subspecialties, fewer than 1% remained inadequate post-augmentation
  • sLLM protocol accuracy (93.1%) was comparable to board-certified radiologists (Rad 3: 91.4%, Rad 4: 92.1%); consistent with prior LLM studies in spine/MSK [2] and CT protocol assignment [3].
  • Critical clinical details absent from original MERs (surgery history, tumour, infections) were extracted and summarised by the sLLM
  • Rule-based script made final protocol decisions — sLLM provided clinical context only, not the decision
  • Near 100% adequate MERs after sLLM augmentation vs 79.6-95.9% clinician-only
  • Protocol accuracy matched experienced radiologists across body, MSK & neuroradiology
  • End-to-end pipeline offers a scalable, standardised protocoling pathway with reduced admin burden
  • Future work: prospective multicentre evaluation, cost-effectiveness & extension to CT / ultrasound
  • Single-centre, retrospective study · outpatient MERs only
  • Not powered for non-inferiority testing
  • Post-deployment guardrails remain essential

References

  1. Wildman-Tobriner B, et al. RI-RADS: A New Standardized Reporting System for the Reason for Exam. J Am Coll Radiol. 2022.
  2. Hitzert MM, et al. Large Language Models for the Automated Vetting of Musculoskeletal MRI Requests. J Digit Imaging. 2024.
  3. Kanemaru N, et al. Efficacy of Fine-Tuned Large Language Model in CT Protocol Assignment as Clinical Decision-Supporting System. J Imaging Inform Med. 2025.

Correspondence: 

Dr James Hallinan, Senior Consultant, Department of Diagnostic Imaging, National University Hospital

Email: james_Hallinan@nuhs.edu.sg

Input

Clinician-generated MRI examination request (MER)

sLLm Augumentation (Claude 3.5)

Retrieves latest clinical entry & imaging reports from EMR · Extracts & summarises key clinical details

Output & Evaluation

Augmented MER + assigned protocol · RI-RADS graded by Rads 1–4

Figure 1: Summary of materials

Figure 2: Flowchart of sLLM augmentation

Figure 3: Study design flowchart. Clinician MERs were augmented using an sLLM (Claude 3.5, Anthropic). Two experienced radiologists (Rads 1 and 2) graded information quality via RI-RADS and provided the protocol accuracy reference standard. The sLLM and two general radiologists (Rads 3 and 4) were evaluated against this standard.

Figure 4: Summary of results of MRI protocoling accuracy for the sLLM and board-certified radiologists versus reference standard. sLLM augmentation nearly eliminated inadequate MRI requests and matched expert radiologist protocol accuracy.

Figure 5: Overall MRI Protocoling accuracy for the sLLM and board-certified radiologists versus reference standard.

Figure 6: MRI protocoling accuracy for the sLLM and board-certified radiologists versus reference standard, broken down into subspecialties

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