Title: IVF After Recurrent Breast Cancer: is it Ethical? A Case Report

 

Case Summary:

•42-year-old Asian woman presents to Recurrent Miscarriage (RM) Clinic with 2 previous 1st trimester miscarriages and subfertility (>2 years to conceive)

•History of breast cancer 2017 and breast cancer recurrence 2020. In remission from recurrence for 3 years.

•Maintenance tamoxifen therapy, stopped herself to try and conceive.

•Oestrogen and Progesterone receptor positive cancer, HER2 negative

•RM bloods all within normal range

•In vitro fertilisation (IVF) would be the optimum chance of successful conception (6% with own eggs - improved odds with donor eggs).

•Concerns raised by fertility, RM and breast team regarding IVF impact on recurrence risk.

•Already at a 5% risk of recurrence due to stopping tamoxifen already.