Outcome of locally practiced method of PGE2 for induction of labour
A prospective audit
Gunathilaka SNMPK, Prasanga DPGGM, Karunananda SA, Rathnayake RMCJ, Jayawardana MAMM
Professorial Unit – Gynaecology & Obstetrics, Teaching Hospital Peradeniya, Sri Lanka.
§Induction of labour - A method of prematurely or artificially stimulating the onset of labour prior to spontaneous onset.
§Best undertaken when continuing the pregnancy is associated with greater maternal or fetal risk than inducing labour.
§ Among several methods, vaginal Prostaglandin E2 (PGE2) is preferred.
§The recommended regimen is 3mg tablet per vagina followed by a second dose after 6 hours if labour is not established. (NICE - July 2008).
§A different regimen is used in the audited setting (3mg of PGE2 followed by a second dose after 24 hours) to suit the local set up, in order to reduce the burden on staff and to optimize monitoring.
To audit the outcome of induction of labour using the local regimen compared to the standards given by NICE.
Materials & Methods
ØCarried out in the Professorial Obstetric Unit in Teaching Hospital Peradeniya.
ØDuration - One month
ØOutcomes of the induction were prospectively obtained using a structured pro forma, of all mothers who underwent induction of labour.
Number of inductions – 79 out of 419 (19%)
Standard – 19.8%
üSuccess rates and major complication rates were similar to the NICE standard.
üCurrent regimen will be followed for induction of labour.