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Comparison of Evoked Paresthesia Between SCS and DRG Stimulation: an ACCURATE Sub-study

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Spinal Cord Stimulation (SCS) is a proven, effective treatment for chronic, intractable pain in a variety of neuropathic pain conditions. A challenge often associated with SCS is the difficulty to target therapy to specific anatomical locations without extraneous stimulation, particularly in patients with complex pain patterns. The dorsal root ganglia (DRG) are the sensory gate of the central nervous system. They are highly organized and segmentally arranged. Therefore, electric stimulation of the DRG, by directly modulating the activity of primary sensory neurons on a spinally segmented basis, can afford a higher degree of specificity in targeting painful areas. In this study we use the paresthesia maps completed by chronic pain patients participating in the ACCURATE™ study to compare the elicited paresthesia between SCS and DRG Stimulation.

This study shows that DRG stimulation can effectively relieve pain while producing, on average, paresthesia which is less frequent, less intense and with a lower footprint, regardless of body position. The study also suggests that DRG stimulation evoked paresthesia is less prone to differ with the changes in body positions as compared to SCS.

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