Oncodermatology specialized clinic at “A. Sygros” University Hospital: Epidemiologic data from the first 2 operational years
Study Purpose: To perform patient population epidemiologic analysis of the “Cutaneous Side Effects of Antineoplastic Treatment Clinic” at the referral center “A. Sygros” Hospital and to study the cutaneous adverse effects of this patient population.
Study Design: All patients examined at the specialized clinic from January 2015 to December 2016 were included.
Results: A total of 265 patients were examined (male: 104, female: 161). The average age of our population was 61,6 [49,1 - 74,1]. The most common malignancies of our patient population were breast cancer (92 patients, 36% of all cases), lung cancer (39 patients, 15%), melanoma (28 patients, 10,5%) and colon cancer (27 patients, 10,2%).
The patients were undergoing classic chemotherapy treatment (80 patients, 30% of all patients), targeted immunotherapy treatment (113 patients, 42,6%), combination of chemotherapy and targeted therapy(35 patients, 13,2%) or had stopped treatment at the time of their visit or were receiving radiation therapy (37 patients, 14%) . The most common cutaneous side effects were alopecia, xerosis, pruritus, nail changes, papulopustular lesions, photodermatitis associated with photosensitivity and palmoplantar hyperkeratosis.
Conclusions: Antineoplastic treatments and especially targeted therapy, can create a wide range of cutaneous side effects. Dermatologist’s role is important in managing effectively these side effects in order to avoid antineoplastic drug dose adjustment or discontinuation and in helping oncology patients maintain a good quality of life.